Respiratory despair is easily the most feared adverse effect of opioids — along with the leading reason for opioid-connected Loss of life. Tramadol’s ceiling effect on μ-opioid receptor activation limits the extent to which it might suppress respiration, even at supratherapeutic doses. This pharmacological ceiling can make it noticeably safer https://dihydrocodeine3082456.tribunablog.com/not-known-factual-statements-about-dihydrocodeine-tablets-30-mg-52529924