This methylation profile is now obtained in the MBL stage3 and stays comparatively steady with time. Nevertheless, some CLL have intratumor variability in sure areas, which can change the expression of several genes and facilitate tumor evolution.71 Of Take note, this variability is greater in U-CLL than in M-CLL and https://mbl7794940.daneblogger.com/31572404/the-best-side-of-mbl77